XHaskell - Adding regular expression types to haskell

Ph.DDOCTOR OF PHILOSOPH

Teleportation for atomic entangled state by entanglement swapping with separate measurements in cavity QED

Experimentally feasible scheme for teleportation of atomic entangled state via entanglement swapping is proposed in cavity quantum electrodynamics (QED) without joint Bell-state measurement (BSM). In the teleportation processes the interaction between atoms and a single-mode nonresonant cavity with the assistance of a strong classical driving field substitute the joint measurements. The discussion of the scheme indicates that it can be realized by current technologies.Comment: 5 pages, no figur

A STUDY ON THE EXTRACTION PROCESS OF ACTIVE INGREDIENTS FROM AKEBIA STEM AND AN ANALYSIS OF THEIR ANTI-GASTRIC CANCER ACTIVITY

The study investigated the extraction process of active ingredients from akebia stem and an analysis of their anti-gastric cancer activity. Three different extraction methods were used to obtain extracts, namely the decoction method (group A), reflux extraction method (group B), and maceration method (group C), of which reflux extraction method and maceration method used ethanol as the extraction solvent, while decoction method used distilled water for extraction. The differences in anti-gastric cancer activity of the three extracts were compared. MTT assay was used to test and compare the inhibitory effects of extracts obtained in A, B, and C groups on gastric cancer cells. The results showed that the dry extract obtained by heat reflux extraction with “water-ethanol” ratio of 1:2, extractant volume of 70 ml, with ethanol as extraction solvent presented the best inhibitory activity on gastric cancer SGC-7901 cells in this study. Its inhibitory effect did not change over time, and was directly proportional to the concentration

Collaborative Knowledge Graph Fusion by Exploiting the Open Corpus

To alleviate the challenges of building Knowledge Graphs (KG) from scratch, a more general task is to enrich a KG using triples from an open corpus, where the obtained triples contain noisy entities and relations. It is challenging to enrich a KG with newly harvested triples while maintaining the quality of the knowledge representation. This paper proposes a system to refine a KG using information harvested from an additional corpus. To this end, we formulate our task as two coupled sub-tasks, namely join event extraction (JEE) and knowledge graph fusion (KGF). We then propose a Collaborative Knowledge Graph Fusion Framework to allow our sub-tasks to mutually assist one another in an alternating manner. More concretely, the explorer carries out the JEE supervised by both the ground-truth annotation and an existing KG provided by the supervisor. The supervisor then evaluates the triples extracted by the explorer and enriches the KG with those that are highly ranked. To implement this evaluation, we further propose a Translated Relation Alignment Scoring Mechanism to align and translate the extracted triples to the prior KG. Experiments verify that this collaboration can both improve the performance of the JEE and the KGF

Region- or state-related differences in expression and activation of extracellular signal-regulated kinases (ERKs) in naïve and pain-experiencing rats

<p>Abstract</p> <p>Background</p> <p>Extracellular signal-regulated kinase (ERK), one member of the mitogen-activated protein kinase (MAPK) family, has been suggested to regulate a diverse array of cellular functions, including cell growth, differentiation, survival, as well as neuronal plasticity. Recent evidence indicates a role for ERKs in nociceptive processing in both dorsal root ganglion and spinal cord. However, little literature has been reported to examine the differential distribution and activation of ERK isoforms, ERK1 and ERK2, at different levels of pain-related pathways under both normal and pain states. In the present study, quantitative blot immunolabeling technique was used to determine the spatial and temporal expression of ERK1 and ERK2, as well as their activated forms, in the spinal cord, primary somatosensory cortex (SI area of cortex), and hippocampus under normal, transient pain and persistent pain states.</p> <p>Results</p> <p>In naïve rats, we detected regional differences in total expression of ERK1 and ERK2 across different areas. In the spinal cord, ERK1 was expressed more abundantly than ERK2, while in the SI area of cortex and hippocampus, there was a larger amount of ERK2 than ERK1. Moreover, phosphorylated ERK2 (pERK2), not phosphorylated ERK1 (pERK1), was normally expressed with a high level in the SI area and hippocampus, but both pERK1 and pERK2 were barely detectable in normal spinal cord. Intraplantar saline or bee venom injection, mimicking transient or persistent pain respectively, can equally initiate an intense and long-lasting activation of ERKs in all three areas examined. However, isoform-dependent differences existed among these areas, that is, pERK2 exhibited stronger response than pERK1 in the spinal cord, whereas ERK1 was more remarkably activated than ERK2 in the S1 area and hippocampus.</p> <p>Conclusion</p> <p>Taken these results together, we conclude that: (1) under normal state, while ERK immunoreactivity is broadly distributed in the rat central nervous system in general, the relative abundance of ERK1 and ERK2 differs greatly among specific regions; (2) under pain state, either ERK1 or ERK2 can be effectively phosphorylated with a long-term duration by both transient and persistent pain, but their response patterns differ from each other across distinct regions; (3) The long-lasting ERKs activation induced by bee venom injection is highly correlated with our previous behavioral, electrophysiological, morphological and pharmacological observations, lending further support to the functional importance of ERKs-mediated signaling pathways in the processing of negative consequences of pain associated with sensory, emotional and cognitive dimensions.</p

Genome-wide analysis of Cushion willow provides insights into alpine plant divergence in a biodiversity hotspot

Funding: Strategic Priority Research Program of Chinese Academy of Sciences (XDA 20050203 (H.S.); Major Program of the NSFC 31590823 (H.S.); National Key R & D Program of China 2017YF0505200 (H.S.); NSFC (31670198 to J.C., 31560062 to Y.H.,31871271 to W.Z.); Science and Technology Research Program of KIB (NO.KIB2016005 to J.C.); Youth Innovation Promotion Association, CAS (J.C.), and Peking-Tsinghua Center for Life Science, the State Key Laboratory of Protein and PlantGene Research and Qidong-SLS Innovation Fund (W.Z.).The Hengduan Mountains (HDM) biodiversity hotspot exhibits exceptional alpine plant diversity. Here, we investigate factors driving intraspecific divergence within a HDM alpine species Salix brachista (Cushion willow), a common component of subnival assemblages. We produce a high-quality genome assembly for this species and characterize its genetic diversity, population structure and pattern of evolution by resequencing individuals collected across its distribution. We detect population divergence that has been shaped by a landscape of isolated sky island-like habitats displaying strong environmental heterogeneity across elevational gradients, combined with population size fluctuations that have occurred since approximately the late Miocene. These factors are likely important drivers of intraspecific divergence within Cushion willow and possibly other alpine plants with a similar distribution. Since intraspecific divergence is often the first step toward speciation, the same factors can be important contributors to the high alpine species diversity in the HDM.Publisher PDFPeer reviewe